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KMID : 1134819970260020308
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Journal of the Korean Society of Food Science and Nutrition
1997 Volume.26 No. 2 p.308 ~ p.313
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Effects of Angelica keiskei on lipid Metabolism in Rats
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Park Jeong-Ro
Park Seok-Kyu
Cho Young-Sook
Chun Soon-Sil
Choi Seong-Hee
Park Jong-Cheol
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Abstract
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To investigate the effects of Angelica keiskei Koidz on cholesterol metabolism, male Sprague Dawley rats were fed diets containing 5% of A keiskei flour for 6 weeks. A keiskei decreased plasma contents of total cholesterol, LDL-cholesterol and triglyceride while showing no change in HDL-cholesterol, resulting in reduction of atherosclerotic index. Decrease in liver concentration of triglyceride and increases in fecal excretion of cholesterol, total neutral steroid and bile acid were also observed. Those results suggest that A keiskei improves hypercholesterolemia through, at least in part, reducing the absorption of cholesterol and enhancing the catabolism of cholesterol to bile acids.
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KEYWORD
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Angelica keiskei Koidz, hypocholesterolemic effect, hypotriglyceridemic effect, fecal steriod excretion
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